EFFECTS OF CHEMOTHERAPEUTİC AGENTS ON SERUM ELECTROLYTE LEVELS IN HEMATOLOGICAL MALIGNANCIES
EFFECTS OF CHEMOTHERAPEUTİC AGENTS ON SERUM ELECTROLYTE LEVELS IN HEMATOLOGICAL MALIGNANCIES
ISSN: 2757-976X ;
E-ISSN: 2757-976X ;
- Year : 2024
- Vol : 4
- No : 1
- Page : 1-6
ÖZ
Aim: This study aimed to investigate the changes in serum levels of various electrolytes on the 1st day of treatment in patients receiving chemotherapy due to hematological malignancies.
Patients and Methods: Serum levels of various electrolytes before and after the first course of chemotherapy were compared retrospectively in patients receiving chemotherapy for hematological malignancies between 2010-2014.
Results: Data from 195 patients were analyzed. Serum calcium concentrations decreased significantly in multiple myeloma (p=0.013), Hodgkin lymphoma (p=0.03) and non-Hodgkin lymphoma (p=0.002) groups after chemotherapy compared to pre-chemotherapy levels. In the chronic lymphocytic lymphoma group sodium (p=0.017) and magnesium (p=0.006) concentrations, in the acute myeloid leukemia group sodium concentration (p=0.012) were decreased significantly after chemotherapy. In the acute lymphoblastic leukemia group, magnesium concentration significantly increased after chemotherapy (p=0.028).
Conclusion: In patients receiving chemotherapy for hematological malignancies significant changes occur in plasma concentrations of serum electrolytes even in the early period after chemotherapy.
Patients and Methods: Serum levels of various electrolytes before and after the first course of chemotherapy were compared retrospectively in patients receiving chemotherapy for hematological malignancies between 2010-2014.
Results: Data from 195 patients were analyzed. Serum calcium concentrations decreased significantly in multiple myeloma (p=0.013), Hodgkin lymphoma (p=0.03) and non-Hodgkin lymphoma (p=0.002) groups after chemotherapy compared to pre-chemotherapy levels. In the chronic lymphocytic lymphoma group sodium (p=0.017) and magnesium (p=0.006) concentrations, in the acute myeloid leukemia group sodium concentration (p=0.012) were decreased significantly after chemotherapy. In the acute lymphoblastic leukemia group, magnesium concentration significantly increased after chemotherapy (p=0.028).
Conclusion: In patients receiving chemotherapy for hematological malignancies significant changes occur in plasma concentrations of serum electrolytes even in the early period after chemotherapy.
Correspondence Address :
ORDU EĞİTİM ARAŞTIRMA HASTANESİ Yoğun Bakım
Email : [email protected]
Cite this Article As : Kerimoğlu E, Asıl M, Çeneli Ö. Hematolojik Malignitelerde Kemoterapi Ajanlarının Serum Elektrolit Düzeylerine Etkisi. Mev Med Sci. 2024; 4(1): 1-6
Description : Yazarların hiçbiri, bu makalede bahsedilen herhangi bir ürün, aygıt veya ilaç ile ilgili maddi çıkar ilişkisine sahip değildir. Araştırma, herhangi bir dış organizasyon tarafından desteklenmedi.Yazarlar çalışmanın birincil verilerine tam erişim izni vermek ve derginin talep ettiği takdirde verileri incelemesine izin vermeyi kabul etmektedirler. None of the authors, any product mentioned in this article, does not have a material interest in the device or drug. Research, not supported by any external organization. grant full access to the primary data and, if requested by the magazine they agree to allow the examination of data.
Email : [email protected]
Cite this Article As : Kerimoğlu E, Asıl M, Çeneli Ö. Hematolojik Malignitelerde Kemoterapi Ajanlarının Serum Elektrolit Düzeylerine Etkisi. Mev Med Sci. 2024; 4(1): 1-6
Description : Yazarların hiçbiri, bu makalede bahsedilen herhangi bir ürün, aygıt veya ilaç ile ilgili maddi çıkar ilişkisine sahip değildir. Araştırma, herhangi bir dış organizasyon tarafından desteklenmedi.Yazarlar çalışmanın birincil verilerine tam erişim izni vermek ve derginin talep ettiği takdirde verileri incelemesine izin vermeyi kabul etmektedirler. None of the authors, any product mentioned in this article, does not have a material interest in the device or drug. Research, not supported by any external organization. grant full access to the primary data and, if requested by the magazine they agree to allow the examination of data.
EFFECTS OF CHEMOTHERAPEUTİC AGENTS ON SERUM ELECTROLYTE LEVELS IN HEMATOLOGICAL MALIGNANCIES, Araştırma Makalesi,
2024, Vol. 4 (1)
2024, Vol. 4 (1)
Received :09.12.2023,
Accepted : 24.04.2024,
Published Online : 26.04.2024
Mevlana Medical Sciences Journal
ISSN: 2757-976X ;
E-ISSN: 2757-976X ;
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Araştırma Makalesi
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Keywords
hematological malignancies, , chemotherapy, sodium, calcium, magnesium